Special Researcher/Tenure-track Associate Professor
Development of CRISPR-associated tools for genome editing and regulation.
Development of genetically-encoded biosensors for screening and dynamic control.
Biosynthesizing high-value added bioproducts via cell factories.
Ruilian Yao#, Di Liu#, Xiao Jia, Yuan Zheng, Wei Liu, Yi Xiao*. (2018) CRISPR-Cas9/Cas12a biotechnology and application in bacteria. Synthetic and Systems Biotechnology. 3(3):135-149
Yi Xiao, Shaojie Wang, Sarah Rommelfanger, Andrea Balassy, Carlos Barba-Ostria, Pengfei Gu, Jonathan M. Galazka, Fuzhong Zhang*. (2018) Developing a Cas9-based tool to engineer native plasmids in Synechocystis sp. PCC 6803. Biotechnology and Bioengineering 115(9):2305-2314.
Yi Xiao, Wen Jiang, Fuzhong Zhang. (2017) Developing a genetically encoded, cross-species biosensor for detecting ammonium and regulating biosynthesis of cyanophycin. ACS Synthetic Biology. 6 (10), pp 1807–1815
Yi Xiao, Christopher H. Bowen, Di Liu, Fuzhong Zhang. (2016) Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis. Nature Chemical Biology 12, 339–344