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7-11InvestigateMolecularBasisofCrosstalkbetweentheCircadianClockandInnateImmunityinArabidopsis

来源:金沙游艺场网址 发布时间 :2014-07-04  阅读次数 :1223

报告题目:Investigate Molecular Basis of Crosstalk between the Circadian Clock and Innate Immunity in Arabidopsis

报 告 ?人:Hua Lu 副教授, University of Maryland Baltimore County

报告时间:7月11日(星期五)11:00-12:30

报告地点:闵行校区生物药学楼3号楼105会议室

联 系 ?人:何亚文,34207941, ? This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

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报告摘要:

The circadian clock integrates temporal information with environmental cues in regulating plant development and physiology. Recently, the circadian clock has been shown to affect plant responses to biotic cues. To further examine this role of the circadian clock, we tested disease resistance in mutants disrupted in CCA1 and LHY, which act synergistically to regulate clock activity. We found that cca1 and lhy mutants also synergistically affect basal and resistance gene-mediated defense against Pseudomonas syringae and Hyaloperonospora arabidopsidis. Disrupting the circadian clock caused by overexpression of CCA1 or LHY also resulted in severe susceptibility to P. syringae. We identified a downstream target of CCA1 and LHY, GRP7, a key constituent of a slave oscillator regulated by the circadian clock and previously shown to influence plant defense and stomatal activity. We show that the defense role of CCA1 and LHY against P. syringae is at least partially through circadian control of stomatal aperture but is independent of defense mediated by salicylic acid. Our data indicate that CCA1 likely acts directly through GRP7 in defense regulation. Furthermore, we found defense activation by P. syringae infection and treatment with the elicitor flg22 can feedback-regulate clock activity. Together these data strongly support a direct role of the circadian clock in defense control and reveal for the first time crosstalk between the circadian clock and plant innate immunity.

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